15Bi15 is a Taoist Medicine framework that examines how ancestral energy, potentially mediated through epigenetic mechanisms, may influence offspring’s physical health, emotional patterns, and spiritual choices. It provides a framework for understanding who we are, transforming what we inherit, cultivating body, mind, and spirit, and fulfilling our life purpose. This Taoist Medicine model integrates fifteen ancestral-spiritual positions with fifteen bodily correspondences, cosmic numerical structures, and the Yi Jing (I Ching) Yin–Yang principle.